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Biological and Preclinical Imaging
Projects
D.1.1 | Coherent diffraction imaging of single particles and biomolecules
D.1.2 | Biological microcrystals and pulsed synchrotron radiation
D.1.3 | Phase-contrast nano-tomography of bones and tissue samples
D.1.4 | Nanoscopy with Broadband Infrared Radiation
D.1.5 | Preclinical phase-contrast imaging of small-animal tumor models
D.1.6 | FemtoSCOPE — a highly resolving two-photon system for diagnosis of cancer (finished)

- The figure shows a phase-contrast microCT image of a small-animal tumor model (mouse). The marked area shows a liver tumor. See project description D.1.5 for more details.
The interdisciplinary research portfolio of D.1 is focused on the translation of modern x-ray physics concepts to biomedical sciences and clinical applications. We are particularly interested in advancing conceptually new approaches for biomedical x-ray imaging and therapy, and work on new kinds of x-ray sources, contrast modalities, and images processing algorithms. Our activities range from fundamental research using state-of-the-art, large-scale x-ray synchrotron and laser facilities to applied research and technology transfer projects aiming at the creation of improved biomedical device technology for clinical use. From a medical perspective, our work currently targets novel imaging concepts for early cancer diagnostics, high-resolution 3D histology, and protein structure determination.
